Epigenetic Silencing of Core Histone Genes by HERS in Drosophila
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چکیده
منابع مشابه
Epigenetic regulatory elements associate with specific histone modifications to prevent silencing of telomeric genes
In eukaryotic cells, transgene expression levels may be limited by an unfavourable chromatin structure at the integration site. Epigenetic regulators are DNA sequences which may protect transgenes from such position effect. We evaluated different epigenetic regulators for their ability to protect transgene expression at telomeres, which are commonly associated to low or inconsistent expression ...
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ژورنال
عنوان ژورنال: Molecular Cell
سال: 2012
ISSN: 1097-2765
DOI: 10.1016/j.molcel.2011.12.029